GLIS2 blocking peptide

Cannot supply to this region.

SKU:: GTX32148-PEP
Additional Names:: Glis Family Zinc Finger 2 , Nkl , Nphp7 , Glis2
Application:: Neutralisation
Concentration:: 200 ug/ml
Physical State:: Liquid
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:: Genetex
Buffer:: PBS, 0.1% BSA, 0.02% Sodium azide.
Immunogen:: GLIS family zinc finger 2
Species:: Human
Synonyms:: GLI-similar 2;Kruppel-like zinc finger protein GLIS2;nephrocystin-7;neuronal Krueppel-like protein;NKL;NPHP7;zinc finger protein GLIS2
Extra Details:: This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear transcription factor with five C2H2-type zinc finger domains. The protein encoded by this gene is widely expressed at low levels in the neural tube and peripheral nervous system and likely promotes neuronal differentiation. It is abundantly expressed in the kidney and may have a role in the regulation of kidney morphogenesis. p120 regulates the expression level of this protein and induces the cleavage of this protein's C-terminal zinc finger domain. This protein also promotes the nuclear translocation of p120. Mutations in this gene cause nephronophthisis (NPHP), an autosomal recessive kidney disease characterized by tubular basement membrane disruption, interstitial lymphohistiocytic cell infiltration, and development of cysts at the corticomedullary border of the kidneys.[provided by RefSeq, Jan 2010]