NLRP13 blocking peptide

Cannot supply to this region.

SKU:: GTX31990-PEP
Additional Names:: Nlr Family Pyrin Domain Containing 13 , Clr19.7 , Nalp13 , Nod14 , Pan13 , Nlrp13
Application:: Neutralisation
Concentration:: 200 ug/ml
Physical State:: Liquid
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:: Genetex
Buffer:: PBS, 0.1% BSA, 0.02% Sodium azide.
Immunogen:: NLR family, pyrin domain containing 13
Species:: Human
Synonyms:: CLR19.7;NACHT, leucine rich repeat and PYD containing 13;NACHT, LRR and PYD containing protein 13;NACHT, LRR and PYD domains-containing protein 13;NALP13;NOD14;nucleotide-binding oligomerization domain protein 14;nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 13;PAN13
Extra Details:: NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP13, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM, Mar 2008]