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GTX31881-PEP

B-Raf blocking peptide

Cannot supply to this region.

SKU:
GTX31881-PEP
Additional Names:
B-Raf Proto-Oncogene, Serine/Threonine Kinase , B-Raf1 , B-Raf , Braf1 , Ns7 , Rafb1 , Braf
Application:
Neutralisation
Concentration:
200 ug/ml
Physical State:
Liquid
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Genetex
Buffer:
PBS, 0.1% BSA, 0.02% Sodium azide.
Immunogen:
B-Raf proto-oncogene, serine/threonine kinase
Species:
Human
Synonyms:
94 kDa B-raf protein;B-raf;B-Raf proto-oncogene serine/threonine-protein kinase (p94);B-Raf serine/threonine-protein;B-RAF1;BRAF1;murine sarcoma viral (v-raf) oncogene homolog B1;NS7;proto-oncogene B-Raf;RAFB1;serine/threonine-protein kinase B-raf;v-raf murine sarcoma viral oncogene homolog B;v-raf murine sarcoma viral oncogene homolog B1
Extra Details:
This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq, Jul 2008]
Shipping Conditions:
Dry Ice