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  2. Polyclonal

GTX31861

PHLPP1 antibody

Cannot supply to this region.

SKU:
GTX31861
Additional Names:
PH domain and leucine rich repeat protein phosphatase 1 , PHLPP , PLEKHE1 , PPM3A , SCOP
Application:
ELISA, WB, IF, ICC
Concentration:
1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human
Buffer:
PBS, 0.02% Sodium azide.
Immunogen:
PHLPP1 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human PHLPP1.The immunogen is located within amino acids 250 - 300 of PHLPP1.
Uniprot:
O60346
Synonyms:
PH domain leucine-rich repeat-containing protein phosphatase 1;PH domain-containing family E member 1;PHLPP;pleckstrin homology domain containing, family E (with leucine rich repeats) member 1;Pleckstrin homology domain-containing family E member 1;PLEKHE1;PPM3A;protein phosphatase, Mg2+/Mn2+ dependent 3A;SCN circadian oscillatory protein;SCOP;suprachiasmatic nucleus circadian oscillatory protein
Extra Details:
This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. [provided by RefSeq, Dec 2011]
Shipping Conditions:
Blue Ice