GTX31836-PEP
ROCK1 blocking peptide
Cannot supply to this region.
- SKU:
- GTX31836-PEP
- Additional Names:
- Rho Associated Coiled-Coil Containing Protein Kinase 1 , P160Rock , Rock-I , Rock1
- Application:
- Neutralisation
- Concentration:
- 200 ug/ml
- Physical State:
- Liquid
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Genetex
- Buffer:
- PBS, 0.1% BSA, 0.02% Sodium azide.
- Immunogen:
- Rho associated coiled-coil containing protein kinase 1
- Species:
- Human
- Synonyms:
- p160 ROCK-1;P160ROCK;renal carcinoma antigen NY-REN-35;rho-associated protein kinase 1;ROCK-I
- Extra Details:
- This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Dry Ice