GTX31810
NOD1 antibody
Cannot supply to this region.
- SKU:
- GTX31810
- Additional Names:
- nucleotide binding oligomerization domain containing 1 , CARD4 , CLR7.1 , NLRC1
- Application:
- ELISA, WB
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- NOD1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy end of human NOD1.The immunogen is located within the last 50 amino acids of NOD1.
- Uniprot:
- Q9Y239
- Synonyms:
- CARD4;caspase recruitment domain family, member 4;caspase recruitment domain-containing protein 4;CLR7.1;NLR family, CARD domain containing 1;NLRC1;nucleotide-binding oligomerization domain-containing protein 1;nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 1
- Extra Details:
- This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Oct 2009]
- Shipping Conditions:
- Blue Ice