GTX31799
Nephrin antibody
Cannot supply to this region.
- SKU:
- GTX31799
- Additional Names:
- NPHS1 adhesion molecule, nephrin , CNF , NPHN , nephrin
- Application:
- ELISA, IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- Nephrin antibody was raised against a 16 amino acid synthetic peptide from near the center of human Nephrin.The immunogen is located within amino acids 870 - 920 of Nephrin.
- Uniprot:
- O60500
- Synonyms:
- CNF;nephrin;nephrosis 1, congenital, Finnish type (nephrin);NPHN;NPHS1, nephrin;renal glomerulus-specific cell adhesion receptor;truncated NPHS1
- Extra Details:
- This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.[provided by RefSeq, Oct 2009]
- Shipping Conditions:
- Blue Ice