GTX31757-PEP
STIM1 blocking peptide
Cannot supply to this region.
- SKU:
- GTX31757-PEP
- Additional Names:
- Stromal Interaction Molecule 1 , D11S4896E , Gok , Imd10 , Strmk , Tam , Tam1 , Stim1
- Application:
- Neutralisation
- Concentration:
- 200 ug/ml
- Physical State:
- Liquid
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Genetex
- Buffer:
- PBS, 0.1% BSA, 0.02% Sodium azide.
- Immunogen:
- stromal interaction molecule 1
- Species:
- Human
- Synonyms:
- D11S4896E;GOK;IMD10;STRMK;stromal interaction molecule 1;TAM;TAM1
- Extra Details:
- This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene.[provided by RefSeq, Jan 2009]
- Shipping Conditions:
- Dry Ice