Bcl2A1 antibody

Cannot supply to this region.

SKU:: GTX31739
Additional Names:: BCL2 related protein A1 , ACC-1 , ACC-2 , ACC1 , ACC2 , BCL2L5 , BFL1 , GRS , HBPA1
Application:: ELISA, WB, IHC-P
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: PBS, 0.02% Sodium azide.
Immunogen:: Bcl2A1 antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human Bcl2A1.The immunogen is located within the first 50 amino acids of Bcl2A1.
Uniprot:: Q16548
Synonyms:: ACC-1;ACC-2;ACC1;ACC2;bcl-2-like protein 5;bcl-2-related protein A1;bcl2-L-5;BCL2L5;BFL1;GRS;HBPA1;hematopoietic BCL2-related protein A1;hemopoietic-specific early response protein;protein BFL-1;Protein GRS
Extra Details:: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Shipping Conditions:: Blue Ice