GTX31738-PEP
Bcl2A1 blocking peptide
Cannot supply to this region.
- SKU:
- GTX31738-PEP
- Additional Names:
- Bcl2 Related Protein A1 , Acc-1 , Acc-2 , Acc1 , Acc2 , Bcl2L5 , Bfl1 , Grs , Hbpa1 , Bcl2A1
- Application:
- Neutralisation
- Concentration:
- 200 ug/ml
- Physical State:
- Liquid
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Genetex
- Buffer:
- PBS, 0.1% BSA, 0.02% Sodium azide.
- Immunogen:
- BCL2 related protein A1
- Species:
- Human
- Synonyms:
- ACC-1;ACC-2;ACC1;ACC2;bcl-2-like protein 5;bcl-2-related protein A1;bcl2-L-5;BCL2L5;BFL1;GRS;HBPA1;hematopoietic BCL2-related protein A1;hemopoietic-specific early response protein;protein BFL-1
- Extra Details:
- This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Dry Ice