GTX31700
Caspase 5 antibody
Cannot supply to this region.
- SKU:
- GTX31700
- Additional Names:
- caspase 5 , ICE(rel)III , ICEREL-III , ICH-3
- Application:
- ELISA, WB
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- Caspase-5 antibody was raised against a 16 amino acid synthetic peptide from the amino-terminus of human Caspase-5.The immunogen is located within amino acids 40 - 90 of Caspase-5.
- Uniprot:
- P51878
- Synonyms:
- caspase 5 variant X1;caspase 5, apoptosis-related cysteine peptidase;caspase 5, apoptosis-related cysteine protease;caspase-5;ICE(rel)-III;ICE(rel)III;ICEREL-III;ICH-3;protease ICH-3;protease TY;TY protease
- Extra Details:
- This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010]
- Shipping Conditions:
- Blue Ice