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GTX31692-PEP

TAB2 blocking peptide

Cannot supply to this region.

SKU:
GTX31692-PEP
Additional Names:
Tgf-Beta Activated Kinase 1 (Map3K7) Binding Protein 2 , Chtd2 , Map3K7Ip2 , Tab-2 , Tab2
Application:
Neutralisation
Concentration:
200 ug/ml
Physical State:
Liquid
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Genetex
Buffer:
PBS, 0.1% BSA, 0.02% Sodium azide.
Immunogen:
TGF-beta activated kinase 1/MAP3K7 binding protein 2
Species:
Human
Synonyms:
CHTD2;MAP3K7IP2;mitogen-activated protein kinase kinase kinase 7-interacting protein 2;TAB-2;TAK1-binding protein 2;TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
Extra Details:
The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. [provided by RefSeq, Jul 2008]
Shipping Conditions:
Dry Ice