GTX31529-PEP
KREMEN2 blocking peptide
Cannot supply to this region.
- SKU:
- GTX31529-PEP
- Additional Names:
- Kringle Containing Transmembrane Protein 2 , Krm2 , Kremen2
- Application:
- Neutralisation
- Concentration:
- 200 ug/ml
- Physical State:
- Liquid
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Genetex
- Buffer:
- PBS, 0.1% BSA, 0.02% Sodium azide.
- Immunogen:
- kringle containing transmembrane protein 2
- Species:
- Human
- Synonyms:
- dickkopf receptor 2;kremen protein 2;kringle domain-containing transmembrane protein 2;kringle-containing protein marking the eye and the nose;KRM2
- Extra Details:
- This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
- Shipping Conditions:
- Dry Ice