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GTX31469-PEP

GRB10 blocking peptide

Cannot supply to this region.

SKU:
GTX31469-PEP
Additional Names:
Growth Factor Receptor Bound Protein 10 , Grb-Ir , Grb-10 , Irbp , Meg1 , Rss , Grb10
Application:
Neutralisation
Concentration:
200 ug/ml
Physical State:
Liquid
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Genetex
Buffer:
PBS, 0.1% BSA, 0.02% Sodium azide.
Immunogen:
growth factor receptor bound protein 10
Species:
Human
Synonyms:
Grb-10;GRB-IR;GRB10 adapter protein;GRB10 adaptor protein;growth factor receptor-bound protein 10;insulin receptor-binding protein Grb-IR;IRBP;maternally expressed gene 1;MEG1;RSS
Extra Details:
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010]
Shipping Conditions:
Dry Ice