GTX31361-PEP
OTUD5 blocking peptide
Cannot supply to this region.
- SKU:
- GTX31361-PEP
- Additional Names:
- Otu Deubiquitinase 5 , Duba , Otud5
- Application:
- Neutralisation
- Concentration:
- 200 ug/ml
- Physical State:
- Liquid
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Genetex
- Buffer:
- PBS, 0.1% BSA, 0.02% Sodium azide.
- Immunogen:
- OTU deubiquitinase 5
- Species:
- Human
- Synonyms:
- deubiquinating enzyme A;deubiquitinating enzyme A;DUBA;MCAND;OTU domain containing 5;OTU domain-containing protein 5
- Extra Details:
- This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2008]
- Shipping Conditions:
- Dry Ice