GTX31306-PEP
TIGAR blocking peptide
Cannot supply to this region.
- SKU:
- GTX31306-PEP
- Additional Names:
- Tp53 Induced Glycolysis Regulatory Phosphatase , C12Orf5 , Fr2Bp , Tigar
- Application:
- Neutralisation
- Concentration:
- 200 ug/ml
- Physical State:
- Liquid
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Genetex
- Buffer:
- PBS, 0.1% BSA, 0.02% Sodium azide.
- Immunogen:
- TP53 induced glycolysis regulatory phosphatase
- Species:
- Human
- Synonyms:
- C12orf5;FR2BP;fructose-2,6-bisphosphatase TIGAR;fructose-2,6-bisphosphate 2-phosphatase;probable fructose-2,6-bisphosphatase TIGAR;TP53-induced glycolysis and apoptosis regulator;transactivated by NS3TP2 protein
- Extra Details:
- This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Dry Ice