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  2. Polyclonal

GTX30812

TYK2 antibody

Cannot supply to this region.

SKU:
GTX30812
Additional Names:
tyrosine kinase 2 , IMD35 , JTK1
Application:
WB, IF, ICC
Physical State:
Liquid
Species Reactivity:
Human
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human
Buffer:
PBS, 15mM Sodium azide.
Immunogen:
synthetic peptide corresponding to amino acids 1046-1060 of human TYK2.
Uniprot:
P29597
Synonyms:
IMD35;JTK1;non-receptor tyrosine-protein kinase TYK2
Extra Details:
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq]
Shipping Conditions:
Blue Ice