GTX30689
NUMB antibody
Cannot supply to this region.
- SKU:
- GTX30689
- Additional Names:
- NUMB endocytic adaptor protein , Nb
- Application:
- WB, IF, ICC
- Concentration:
- 3.5 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Mouse
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Tris-Glycine, 150mM NaCl, 0.05% Sodium azide.
- Immunogen:
- A synthetic peptide made to a C-terminal region of mouse NUMB (between residues 600-653). [UniProt# Q9QZS3]
- Uniprot:
- Q9QZS3
- Synonyms:
- m-num;Nb;numb gene homolog;numb homolog;protein numb homolog
- Extra Details:
- Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.
- Shipping Conditions:
- Blue Ice