GTX30601
POT1 antibody
Cannot supply to this region.
- SKU:
- GTX30601
- Additional Names:
- protection of telomeres 1 , CMM10 , GLM9 , HPOT1
- Application:
- WB
- Concentration:
- 2.25 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Tris-Glycine, 150mM NaCl, 0.05% Sodium azide.
- Immunogen:
- A synthetic peptide made to an internal portion of the human POT1 protein sequence (between residues 200-300). [UniProt# Q9NUX5]
- Uniprot:
- Q9NUX5
- Synonyms:
- CMM10;GLM9;HPOT1;POT1-like telomere end-binding protein;protection of telomeres 1 homolog;protection of telomeres protein 1
- Extra Details:
- This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq]
- Shipping Conditions:
- Blue Ice