Daxx antibody [DAXX-01]

Cannot supply to this region.

SKU:: GTX29091
Additional Names:: BING2 , DAP6 , DAXX , EAP1 , death domain associated protein
Application:: WB, IF, ICC
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein A Purified
Storage Conditions:: 2-8[o]C Do not freeze.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, 15mM Sodium azide.
Immunogen:: Recombinant C-terminal part (aa 558-740) of human Daxx.
Clone:: DAXX-01
Uniprot:: Q9UER7
Synonyms:: BING2;CENP-C binding protein;DAP6;Daxx;death domain-associated protein 6;death-associated protein 6;EAP1;ETS1-associated protein 1;fas death domain-associated protein;Fas-binding protein;SMIM40
Extra Details:: This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]

Shipping Conditions:: Blue Ice