GTX28461
RAIDD peptide
Cannot supply to this region.
- SKU:
- GTX28461
- Additional Names:
- Casp2 And Ripk1 Domain Containing Adaptor With Death Domain , Mrt34 , Raidd , Cradd
- Application:
- Neutralisation
- Concentration:
- 0.20 mg/ml
- Physical State:
- Liquid
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Genetex
- Buffer:
- PBS, 0.1% BSA, 0.02% Sodium azide.
- Immunogen:
- CASP2 and RIPK1 domain containing adaptor with death domain
- Species:
- Human
- Synonyms:
- caspase and RIP adaptor with death domain;CRADD/LYZ fusion;death adaptor molecule RAIDD;death domain containing protein CRADD;death domain-containing protein CRADD;MRT34;RAIDD;RIP-associated ICH1/CED3-homologous protein with death domain
- Extra Details:
- Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNFfamily through their death domain (DD) containing receptors, TNFR1 and Fas. The death signals are transduced by a group of DD containing adapter molecules. A novel cell death adapter was recently identified by two independent groups and designated RAIDD (RIP associated ICH1/CED3 homologous protein with DD) and CRADD (caspase and RIP adapter with DD). RAIDD contains a DD and a CARD (for caspase recruitment domain) which interact with RIP and caspase, respectively, to transduce death signals. RAIDD is constitutively expressed in many tissues and mediates apoptosis caused by Fas and TNFR1.
- Shipping Conditions:
- Dry Ice