GTX28446
DR4 peptide
Cannot supply to this region.
- SKU:
- GTX28446
- Additional Names:
- Tnf Receptor Superfamily Member 10A , Apo2 , Cd261 , Dr4 , Trailr-1 , Trailr1 , Tnfrsf10A
- Application:
- Neutralisation
- Concentration:
- 0.20 mg/ml
- Physical State:
- Liquid
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Genetex
- Buffer:
- PBS, 0.1% BSA, 0.02% Sodium azide.
- Immunogen:
- tumor necrosis factor receptor superfamily, member 10a
- Species:
- Human
- Synonyms:
- APO2;CD261;cytotoxic TRAIL receptor;death receptor 4;DR4;TNF-related apoptosis-inducing ligand receptor 1;TRAIL receptor 1;TRAIL-R1;TRAILR-1;TRAILR1;tumor necrosis factor receptor superfamily member 10A;tumor necrosis factor receptor superfamily member 10a variant 2;tumor necrosis factor receptor superfamily, member 10a
- Extra Details:
- Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel cell death receptor was recently identified and designated DR4 (for death receptor 4). The ligand for this novel death receptor has been identified and termed TRAIL, which is a new member in the TNF family. DR4 is also called TRAIL receptor 1(TRAIL R1). DR4 is expressed in most of human tissues including spleen, peripheral blood leukocytes, small intestine and thymus. Like TNFR1, Fas and DR3, DR4 mediates apoptosis and NF kB activation in many tissues and cells.
- Shipping Conditions:
- Dry Ice