BCL10 peptide

Cannot supply to this region.

SKU:: GTX28430
Additional Names:: B Cell Cll/Lymphoma 10 , Carmen , Ciper , Clap , Imd37 , C-E10 , Me10 , Bcl10
Application:: Neutralisation
Concentration:: 0.20 mg/ml
Physical State:: Liquid
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Genetex
Buffer:: PBS, 0.1% BSA, 0.02% Sodium azide.
Immunogen:: B-cell CLL/lymphoma 10
Species:: Human
Synonyms:: B cell CLL/lymphoma 10;B-cell lymphoma/leukemia 10;c-E10;CARD containing molecule enhancing NF-kB;CARD-containing apoptotic signaling protein;CARD-containing molecule enhancing NF-kappa-B;CARD-containing proapoptotic protein;CARMEN;caspase-recruiting domain-containing protein;cCARMEN;CED-3/ICH-1 prodomain homologous E10-like regulator;cellular homolog of vCARMEN;cellular-E10;CIPER;CLAP;hCLAP;IMD37;mammalian CARD-containing adapter molecule E10;mE10
Extra Details:: Bcl10, also designated as CIPER, mE10, cE10, CARMEN, and CLAP, is an N-terminal CARD (Caspase Recruitment Domain) containing protein. It is a cellular homologue of the equine herpesvirus-2 protein E-10 (vCLAP). Bcl 10 was implicated in the regulation of apoptosis by interacting with caspase 9, enhancing procaspase 9 processing, and triggering its activation when overexpressed in the cell. Bcl10 cellular overexpression induces JNK, p38, and NF-kappaB activation. Deregulation of Bcl10 expression was also demonstrated to be involved in cellular oncogenesis.