GTX28384
MADD peptide
Cannot supply to this region.
- SKU:
- GTX28384
- Additional Names:
- Map Kinase Activating Death Domain , Denn , Ig20 , Rab3Gep , Madd
- Application:
- Neutralisation
- Concentration:
- 0.20 mg/ml
- Physical State:
- Liquid
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Genetex
- Buffer:
- PBS, 0.1% BSA, 0.02% Sodium azide.
- Immunogen:
- MAP-kinase activating death domain
- Species:
- Human
- Synonyms:
- DEEAH;DENN;differentially expressed in normal and neoplastic cells;IG20;insulinoma glucagonoma clone 20;MAP kinase-activating death domain protein;NEDDISH;Rab3 GDP/GTP exchange factor;rab3 GDP/GTP exchange protein;RAB3GEP;RabGEF
- Extra Details:
- Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
- Shipping Conditions:
- Dry Ice