GTX28383
DAP Kinase 3 peptide
Cannot supply to this region.
- SKU:
- GTX28383
- Additional Names:
- Death Associated Protein Kinase 3 , Dlk , Zip , Zipk , Dapk3
- Application:
- Neutralisation
- Concentration:
- 0.20 mg/ml
- Physical State:
- Liquid
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Genetex
- Buffer:
- PBS, 0.1% BSA, 0.02% Sodium azide.
- Immunogen:
- death-associated protein kinase 3
- Species:
- Human
- Synonyms:
- DAP kinase 3;DAP-like kinase;death-associated protein kinase 3;DLK;MYPT1 kinase;ZIP;ZIP-kinase;ZIPK;zipper-interacting protein kinase
- Extra Details:
- Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certainserine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. A novel serine/threonine kinase that mediates apoptosis was recently identified and designated ZIP kinase. ZIP kinase contains an N-terminal kinase domain and a C-terminal leucine zipperstructure and binds to ATF4 that is a member of ATF/CREBfamily. ZIP kinase has high sequence homology to DAP kinase (death-associated protein kinase), which is a mediator of apoptosis induced by gamma interferon. Overexpression of ZIP kinase induces apoptosis. ZIP and DAP kinases represent a novel kinase family, which mediates apoptosis through their catalytic activities. The messenger RNA was ubiquitously expressed in various tissues.
- Shipping Conditions:
- Dry Ice