NOL3 peptide

Cannot supply to this region.

SKU:: GTX28372
Application:: Neutralisation
Concentration:: 0.20 mg/ml
Physical State:: Liquid
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Genetex
Buffer:: PBS, 0.1% BSA, 0.02% Sodium azide.
Species:: Human
Synonyms:: ARC;FCM;muscle-enriched cytoplasmic protein;MYOCL1;MYP;NOP;NOP30;nucleolar protein 3;nucleolar protein 3 (apoptosis repressor with CARD domain);nucleolar protein of 30 kDa
Extra Details:: Nucleolar protein 30 (Nop30) is coded by the Arc gene. The nuclear isoform of Nop30 (1/Nop30)may be involved in RNA splicing and the cytoplasmic isoform (2/Myp) may inhibit apoptosis. Isoform 1 oligomerizes and binds to SFRS9/SRp30C and also interacts with NPM1. Isoform 2 binds caspase 2, caspase 8 and CED3 and inhibits caspase 8 activity. Nop30 isoform 1 is found in nucleoli and nucleoplasm. Nop30 isoform 2 is cytoplasmic. Nop30 is highly expressed in heart and skeletal muscle with lower levels detected in placenta, liver, kidney and pancreas.