GTX28370
Acinus peptide
Cannot supply to this region.
- SKU:
- GTX28370
- Additional Names:
- Apoptotic Chromatin Condensation Inducer 1 , Acinus , Acn , Fsap152 , Acin1
- Application:
- Neutralisation
- Concentration:
- 0.20 mg/ml
- Physical State:
- Liquid
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Genetex
- Buffer:
- PBS, 0.1% BSA, 0.02% Sodium azide.
- Immunogen:
- apoptotic chromatin condensation inducer 1
- Species:
- Human
- Synonyms:
- ACINUS;ACN;apoptotic chromatin condensation inducer in the nucleus;fSAP152;functional spliceosome-associated protein 152
- Extra Details:
- Chromatin condensation and nuclear fragmentation (CCNF)is the hallmark of apoptosis. CCNF is triggered by the activation of members of caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE. A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus). Acinus is cleaved by caspase-3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Acinus is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse and designated AcinusL, AcinusS and AcinusS.
- Shipping Conditions:
- Dry Ice