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  2. Monoclonal

GTX28320

IL1 beta antibody [11E5]

Cannot supply to this region.

SKU:
GTX28320
Additional Names:
interleukin 1 beta , IL-1 , IL1-BETA , IL1F2
Application:
ELISA, IHC
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Protein A Purified
Storage Conditions:
2-8[o]C
Supplier:
Genetex
Host:
Mouse
Reactivities:
Human
Buffer:
PBS, 0.09% Sodium azide.
Immunogen:
Recombinant human IL-1, beta.
Clone:
11E5
Uniprot:
P01584
Synonyms:
catabolin;IL-1;IL-1 beta;IL1-BETA;IL1beta;IL1F2;interleukin 1beta;interleukin-1 beta;preinterleukin 1 beta;pro-interleukin-1-beta
Extra Details:
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
Shipping Conditions:
Blue Ice