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  2. Polyclonal

GTX28132

Neurofibromin antibody

Cannot supply to this region.

SKU:
GTX28132
Additional Names:
neurofibromin 1 , NFNS , VRNF , WSS
Application:
WB, IHC-P, IHC-Fr, IF, ICC
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Unpurified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Serum, 0.02% Sodium azide.
Immunogen:
An N-terminal peptide of Neurofibromin 1 (within amino acids 1-50). [UniProt# P21359]
Uniprot:
P21359
Synonyms:
neurofibromatosis 1;neurofibromatosis-related protein NF-1;neurofibromin;NFNS;truncated neurofibromin 1;VRNF;WSS
Extra Details:
This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq]
Shipping Conditions:
Blue Ice