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GTX28016

p27 Kip1 peptide

Cannot supply to this region.

SKU:
GTX28016
Additional Names:
cyclin dependent kinase inhibitor 1B , CDKN4 , KIP1 , MEN1B , MEN4 , P27KIP1
Application:
IP
Concentration:
0.2 mg/ml
Physical State:
Liquid
Storage Conditions:
2-8[o]C Do not freeze. Aliquot. Store undiluted.
Supplier:
Genetex
Buffer:
PBS, BSA, 0.1% Sodium azide.
Immunogen:
cyclin dependent kinase inhibitor 1B
Species:
Human
Uniprot:
P46527
Synonyms:
CDKN4;cyclin-dependent kinase inhibitor 1B;cyclin-dependent kinase inhibitor 1B (p27, Kip1);Cyclin-dependent kinase inhibitor p27;KIP1;MEN1B;MEN4;P27KIP1
Extra Details:
This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). [provided by RefSeq, Apr 2014]
Shipping Conditions:
Blue Ice