GTX27993
JNK1 peptide
Cannot supply to this region.
- SKU:
- GTX27993
- Additional Names:
- mitogen-activated protein kinase 8 , JNK , JNK-46 , JNK1 , JNK1A2 , JNK21B1/2 , PRKM8 , SAPK1 , SAPK1c
- Application:
- IP
- Concentration:
- 0.2 mg/ml
- Physical State:
- Liquid
- Storage Conditions:
- 2-8[o]C Aliquot. Store undiluted.
- Supplier:
- Genetex
- Buffer:
- PBS, BSA, 0.1% Sodium azide.
- Immunogen:
- mitogen-activated protein kinase 8
- Species:
- Human
- Uniprot:
- P45983
- Synonyms:
- c-Jun N-terminal kinase 1;JNK;JNK-46;JNK1;JNK1A2;JNK21B1/2;JUN N-terminal kinase;MAP kinase 8;mitogen-activated protein kinase 8;PRKM8;SAPK1;SAPK1c;stress-activated protein kinase 1;stress-activated protein kinase 1c;Stress-activated protein kinase JNK1
- Extra Details:
- The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016]
- Shipping Conditions:
- Blue Ice