IKK alpha peptide

Cannot supply to this region.

SKU:: GTX27892
Additional Names:: Conserved Helix-Loop-Helix Ubiquitous Kinase , Ikbka , Ikk-Alpha , Ikk1 , Ikka , Nfkbika , Tcf16 , Chuk
Application:: Neutralisation
Concentration:: 0.20 mg/ml
Physical State:: Liquid
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Genetex
Buffer:: PBS, 0.1% BSA, 0.02% Sodium azide.
Immunogen:: conserved helix-loop-helix ubiquitous kinase
Species:: Human
Synonyms:: BPS2;conserved helix-loop-helix ubiquitous kinase;I-kappa-B kinase 1;I-kappa-B kinase-alpha;IkB kinase alpha subunit;IKBKA;IKK-a kinase;IKK-alpha;IKK1;IKKA;inhibitor of nuclear factor kappa-B kinase subunit alpha;NFKBIKA;Nuclear factor NFkappaB inhibitor kinase alpha;TCF-16;TCF16;transcription factor 16
Extra Details:: Nuclear factor kappa B (NFkB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NFkB mediates the expression of a great variety of genes in response to extracellular stimuli including IL1, TNFa, and bacteria product LPS. NFkB is associated with IkB proteins in the cell cytoplasm, which inhibit NFkB activity. IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKK alpha and IKK beta). IKK alpha and IKK beta interact with each other and both are essential for the NFkB activation. IKK alpha specifically phosphorylates IkBa. IKKa is expressed in variety of human tissues.