Skip to content

View Spec Sheet

open_in_new
  1. Shop all
  2. Polyclonal

GTX27778

Collagen III antibody

Cannot supply to this region.

SKU:
GTX27778
Additional Names:
collagen type III alpha 1 chain , EDS4A , EDSVASC
Application:
ELISA, Flow Cytometry, WB, IHC-P, IHC-Fr, IF, ICC, IP, Dot blot
Concentration:
1.16 mg/ml
Physical State:
Liquid
Species Reactivity:
Bovine, Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Bovine, Human, Mouse, Porcine
Buffer:
20mM Potassium Phosphate, 150mM NaCl, 0.01% Sodium azide.
Immunogen:
Collagen Type III from human and bovine placenta
Uniprot:
P02461
Synonyms:
alpha-1 type III collagen;alpha1 (III) collagen;collagen alpha-1(III) chain;collagen, fetal;collagen, type III, alpha 1;EDS4A;EDSVASC;Ehlers-Danlos syndrome type IV, autosomal dominant;PMGEDSV
Extra Details:
These antibodies are well suited to detect extracellular matrix proteins in normal as well as disease state tissues. Disruption of tissue organization is the hallmark of neoplasia. Malignant lesions can be distinguished from benign by examining the breakdown of basement membranes and loss of 3-dimensional architecture. Malignant cells are presumed to use matrix metalloproteases to degrade barriers created by the extracellular matrix, which then allows metastasis to occur. Collagenases, stomelysins and gelatinases can collectively degrade all of the various components of the extracellular matrix, including fibrillar and non-fibrillar collagens and basement membrane glycoproteins.
Shipping Conditions:
Blue Ice