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  2. Monoclonal

GTX27761

C-Peptide antibody [C-PEP-01]

Cannot supply to this region.

SKU:
GTX27761
Additional Names:
insulin , IDDM , IDDM1 , IDDM2 , ILPR , IRDN , MODY10
Application:
ELISA, RIA, IHC-P, IF, ICC
Concentration:
1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Purified
Storage Conditions:
2-8[o]C Do not freeze.
Supplier:
Genetex
Host:
Mouse
Reactivities:
Human
Buffer:
PBS, 15mM Sodium azide.
Immunogen:
Human C-peptide conjugated to bovine serum albumin.
Clone:
C-PEP-01
Uniprot:
P01308
Synonyms:
IDDM;IDDM1;IDDM2;ILPR;insulin;IRDN;MODY10;PNDM4;preproinsulin;proinsulin
Extra Details:
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Shipping Conditions:
Blue Ice