GTX27635
alpha 1 Antitrypsin antibody (HRP)
Cannot supply to this region.
- SKU:
- GTX27635
- Additional Names:
- serpin family A member 1 , A1A , A1AT , AAT , PI , PI1 , PRO2275 , alpha1AT , nNIF
- Application:
- ELISA, IHC, WB
- Concentration:
- 10 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Goat
- Reactivities:
- Human
- Buffer:
- 20mM Potassium Phosphate, 150mM NaCl, 1% BSA, 0.01% Gentamicin Sulfate.
- Immunogen:
- Alpha 1-Anti-Trypsin collected from human plasma
- Uniprot:
- P01009
- Synonyms:
- A1A;A1AT;AAT;alpha-1 antitrypsin;alpha-1 protease inhibitor;alpha-1 proteinase inhibitor;alpha-1-antiproteinase;alpha-1-antitrypsin;alpha-1-antitrypsin short transcript variant 1C4;alpha-1-antitrypsin short transcript variant 1C5;alpha1AT;anti-elastase;epididymis secretory sperm binding protein;nNIF;PI;PI1;PRO2275;protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin;serine (or cysteine) proteinase inhibitor, clade A, member 1;serpin A1;serpin peptidase inhibitor clade A (alpha-1antiproteinase, antitrypsin) member 1;serpin peptidase inhibitor clade A member 1;serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
- Extra Details:
- Alpha 1 Antitrypsin is a plasma protein synthesised in the liver. It consists of a single polypeptide chain and has a molecular weight of 52 kDa. A serine protease inhibitor, its primary function is the protection of lung tissue from the action of neutrophil elastase. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin. Short peptide from AAT (SPAAT) is a reversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. Its major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE). The average level of alpha 1 Antitrypsin in plasma is 1.3 g/l.
- Shipping Conditions:
- Blue Ice