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  2. Polyclonal

GTX27355

Acinus antibody

Cannot supply to this region.

SKU:
GTX27355
Additional Names:
ACIN1 , ACINUS , ACN , apoptotic chromatin condensation inducer 1 , fSAP152 , Acinus
Application:
ELISA, WB, IF, ICC
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human
Buffer:
PBS, 0.02% Sodium azide.
Immunogen:
Peptide corresponding to aa 994- 1009 of human AcinusL, aa 236-251 of human Acinus S and aa 267-282 of human AcinusS' which are identical to those of mouse Acinus. These sequences are located near the N-terminus of active peptide p17.
Uniprot:
Q9UKV3
Synonyms:
ACINUS;ACN;apoptotic chromatin condensation inducer in the nucleus;fSAP152;functional spliceosome-associated protein 152
Extra Details:
Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
Shipping Conditions:
Blue Ice