CXCR4 antibody

Cannot supply to this region.

SKU:: GTX27199
Additional Names:: C-X-C Motif Chemokine Receptor 4 , Cxcr4
Application:: Flow Cytometry, IHC, WB
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Mouse, Rat
Purification:: Protein A Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Mouse, Rat
Buffer:: PBS, 0.1% Sodium azide.
Immunogen:: Recombinant full length protein (Rat).
Synonyms:: C-X-C chemokine receptor type 4;chemokine (C-X-C motif) receptor 4;chemokine receptor (LCR1);CXC chemokine receptor;CXC-R4;CXCR-4;fusin;LESTR;leukocyte-derived seven transmembrane domain receptor;SDF-1 receptor;stromal cell-derived factor 1 receptor
Extra Details:: CXCR4 (fusin) is one of the members in the seven-transmembrane G-protein-coupled chemokine receptor family. The full-length cDNA was isolated from a human spleen cDNA library (ref 1). Its ligand is chemokine stroma-derived factor (SDF). CXCR4 has been proved to be the co-receptor forHIV-2's binding to CD4 through envelope glycoprotein gp 120 (ref 2). In other cases, CXCR4 can even function as the only receptor for HIV-2's binding to the CD4 host cells (ref 3). Mouse monoclonal antibody (12G5) to CXCR4 has been shown to inhibit HIV infectivity and HIV-induced syncytium.