GTX26314
Cathepsin L antibody [33/2]
Cannot supply to this region.
- SKU:
- GTX26314
- Additional Names:
- cathepsin L , CATL , CTSL1 , MEP
- Application:
- ELISA, WB, IHC-Fr
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Unpurified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Mouse
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Ascites, 15mM Sodium azide.
- Immunogen:
- procathepsin L isolated from the human lung cancer cell line EPLC 32M1.
- Clone:
- 33/2
- Uniprot:
- P07711
- Synonyms:
- Cathepsin L;cathepsin L1;CATL;CTSL1;major excreted protein;MEP;procathepsin L
- Extra Details:
- Cathepsins are lysosomal proteases that play an important role in the intracellular degradation of exogenous and endogenous proteins, activation of enzyme precursors, and tumor invasion and metastasis. Normally located in lysosomes of almost all mammalian cells, they can be secreted from the cell under certain conditions. Cathepsin L is responsible for most of the intra-lysosomal breakdown of normal cells. Cathepsin L is secreted by numerous transformed cells in its inactive pro-form, and mRNA expression level seems to correlate with their metastatic potential.
- Shipping Conditions:
- Blue Ice