Collagen I antibody [COL-1]

Cannot supply to this region.

SKU:: GTX26308
Additional Names:: collagen type I alpha 1 chain
Application:: ELISA, IHC, WB, IHC-P, IHC-Fr, IF, ICC, IP, Dot blot
Physical State:: Liquid
Species Reactivity:: Bovine
Purification:: Unpurified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Bovine, Human, Mouse, Porcine, Rabbit, Rat
Buffer:: Ascites, 15mM Sodium azide.
Immunogen:: bovine skin collagen type I
Clone:: COL-1
Uniprot:: P02453
Synonyms:: alpha-1 type I collagen;collagen alpha-1(I) chain;collagen, type I, alpha 1
Extra Details:: Collagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet repeat that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.