GTX26231
IRAK3 peptide
Cannot supply to this region.
- SKU:
- GTX26231
- Additional Names:
- Interleukin 1 Receptor Associated Kinase 3 , Asrt5 , Irakm , Irak3
- Application:
- Neutralisation
- Concentration:
- 0.20 mg/ml
- Physical State:
- Liquid
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Genetex
- Buffer:
- PBS, 0.1% BSA, 0.02% Sodium azide.
- Immunogen:
- interleukin-1 receptor-associated kinase 3
- Species:
- Human
- Synonyms:
- ASRT5;IL-1 receptor-associated kinase M;inactive IL-1 receptor-associated kinase 3;interleukin-1 receptor-associated kinase 3;IRAKM
- Extra Details:
- Interleukin-1 (IL-1) and lipopolysaccharide (LPS) induce cellular response through IL-1 receptor (IL-1R) and Toll like receptors (TLR). IL-1 receptor-associated kinase (IRAK and IRAK2) mediates the activation of NF-kB by IL-1/Toll receptors, which is a pivotal transcription factor mediating inflammatory and immune response. A novel member in the IRAK/Pelle family was recently identified and designated IRAK-M. IRAKs associate with IL-1/Toll receptors after IL-1 or LPS stimulation and the dominant negative mutants of IRAKs inhibit IL-1 or LPS induced NF-kB activation. Members in IRAK/Pelle family play a central role in IL-1R/TLR mediated inflammatory responses to cytokine IL-1 and LPS.
- Shipping Conditions:
- Dry Ice