GTX26230
IRAK1 peptide
Cannot supply to this region.
- SKU:
- GTX26230
- Additional Names:
- Interleukin 1 Receptor Associated Kinase 1 , Irak , Pelle , Irak1
- Application:
- Neutralisation
- Concentration:
- 0.20 mg/ml
- Physical State:
- Liquid
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Genetex
- Buffer:
- PBS, 0.1% BSA, 0.02% Sodium azide.
- Species:
- Human
- Synonyms:
- interleukin-1 receptor-associated kinase 1;IRAK;IRAK-1;pelle;Pelle homolog
- Extra Details:
- Nuclear factor kappa B (NF-kB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFa and LPS. A serine/threonine protein kinase associated with IL-1 receptor (IRAK) and its homologue mouse pelle-like protein kinase (mPLK) were identified recently. IRAK is associated with the IL-1 receptor subunits IL-1RI and IL-1RAcP after IL-1 binding and serves as a signaling molecule to mediate IL-1 response. IRAK mediates a signaling cascade leading to NF-kB activation by members in the IL-1 family including IL-1 and a novel cytokine IL-18 (also termed IGIF).
- Shipping Conditions:
- Dry Ice