IL22 Receptor alpha 1 peptide

Cannot supply to this region.

SKU:: GTX26227
Additional Names:: Interleukin 22 Receptor Subunit Alpha 1 , Crf2-9 , Il22R , Il22R1 , Il22Ra1
Application:: Neutralisation
Concentration:: 0.20 mg/ml
Physical State:: Liquid
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Genetex
Buffer:: PBS, 0.1% BSA, 0.02% Sodium azide.
Species:: Human
Synonyms:: CRF2-9;cytokine receptor class-II member 9;cytokine receptor family 2 member 9;IL-22 receptor subunit alpha-1;IL-22R-alpha-1;IL-22RA1;IL22R;IL22R1;interleukin 22 receptor, alpha 1;interleukin-22 receptor subunit alpha-1;zcytoR11
Extra Details:: A novel cytokine, designated IL-TIF for IL-10 related T cell derived inducible factor and IL-22, was recently identified. The receptor for IL-22 (IL-22R, also termed CRF2-9 and IL-TIF-R1 chain) is a new member of the class II cytokine receptor family. IL-22R forms a complex with IL-10 receptor b chain and mediates IL-22 signaling. IL-22 and its receptor activate JAK-STAT signaling pathway. IL22R is expressed in normal liver and kidney and their cell lines HepG2 and TK-10. A soluble form of IL-22 receptor, also termed IL-22 binding protein (IL-22BP) and IL-22 receptor-a2 (IL-22RA2), was identified very recently. IL-22BP prevents binding of IL-22 to the functional cell surface IL-22R complex and neutralizes IL-22 activity. LPS induces IL-22 expression, which indicates the role of IL-22 in inflammatory response.