GTX26104
IL1RAP blocking peptide
Cannot supply to this region.
- SKU:
- GTX26104
- Additional Names:
- Interleukin 1 Receptor Accessory Protein , C3Orf13 , Il-1Racp , Il1R3 , Il1Rap
- Concentration:
- 0.20 mg/ml
- Physical State:
- Liquid
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Genetex
- Buffer:
- PBS, 0.1% BSA, 0.02% Sodium azide.
- Immunogen:
- interleukin 1 receptor accessory protein
- Species:
- Human
- Synonyms:
- C3orf13;IL-1 receptor accessory protein;IL-1RAcP;IL1R3;interleukin-1 receptor 3;interleukin-1 receptor accessory protein;interleukin-1 receptor accessory protein beta
- Extra Details:
- The pro-inflammatory cytokine IL-1 induced cellular response requires two subunits of its receptor, IL-1receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAP). IL-1RAP forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor associated kinase (IRAK), which mediates activation of NF-kB inducing kinae (NIK) and of NF-kB, recruits to the IL-1Rcomplex through IL-1RAP. IL-1 activation of stress activated protein kinase and of acid sphingomyelinase also requires IL-1RAP. Like IL-1RI, IL-1RAP subunit is essential for IL-1 mediated cellular response. IL-1RAP is expressed in many tissues.
- Shipping Conditions:
- Dry Ice