BAFF Receptor peptide

Cannot supply to this region.

SKU:: GTX26086
Additional Names:: Tnf Receptor Superfamily Member 13C , Baff-R , Baffr , Bromix , Cd268 , Cvid4 , Prolixin , Tnfrsf13C
Application:: Neutralisation
Concentration:: 0.20 mg/ml
Physical State:: Liquid
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Genetex
Buffer:: PBS, 0.1% BSA, 0.02% Sodium azide.
Species:: Human
Synonyms:: B cell-activating factor receptor;BAFF receptor;BAFF-R;BAFFR;BLyS receptor 3;BROMIX;CD268;CVID4;prolixin;tumor necrosis factor receptor superfamily member 13C
Extra Details:: Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF, BLyS, TALL-1, THANK, and zTNF4. BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. Two receptors, TACI and BCMA, for BAFF were originally identified. A third receptor was identified recently and designated BAFF-R and BR3 for BLyS receptor 3. Unlike BCMA and TACI, which bind to BAFF and April, BAFF-R/BR3 is specific for BAFF and plays a predominant role in BAFF induced B cell development and survival. BAFF and its receptors are involved in B cell associated autoimmune diseases, and activate NF-kappaB and c-jun N terminal kinase.