GTX25692
CIDE A antibody
Cannot supply to this region.
- SKU:
- GTX25692
- Additional Names:
- CIDEA , cell deathinducing DFFAlike effector a , CIDE A , cell death inducing DFFA like effector a
- Application:
- ELISA, WB, IHC-P
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- Peptide corresponding to aa 200-217 of human CIDE-A (accession no. AF041378)
- Uniprot:
- O60543
- Synonyms:
- cell death activator CIDE-A;Cell death-inducing DFFA-like effector A;CIDE-A
- Extra Details:
- This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified. [provided by RefSeq, Aug 2010]
- Shipping Conditions:
- Blue Ice