GTX25511
PDGF Receptor beta antibody
Cannot supply to this region.
- SKU:
- GTX25511
- Additional Names:
- platelet derived growth factor receptor beta , CD140B , IBGC4 , IMF1 , JTK12 , KOGS , PDGFR , PDGFR-1 , PDGFR1 , PENTT
- Application:
- Flow Cytometry, WB, IHC-P, IF, ICC
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- SAS Precipitated; Dialysis
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 0.09% Sodium azide.
- Immunogen:
- KLH conjugated synthetic peptide between 40-72 amino acids from the N-terminal region of human PDGFRB.
- Uniprot:
- P09619
- Synonyms:
- Activated tyrosine kinase PDGFRB;Beta platelet-derived growth factor receptor;beta-type platelet-derived growth factor receptor;CD140 antigen-like family member B;CD140B;IBGC4;IMF1;JTK12;KOGS;NDEL1-PDGFRB;PDGF-R-beta;PDGFR;PDGFR-1;PDGFR-beta;PDGFR1;PENTT;platelet-derived growth factor receptor 1;platelet-derived growth factor receptor beta;platelet-derived growth factor receptor, beta polypeptide
- Extra Details:
- The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Aug 2017]
- Shipping Conditions:
- Blue Ice