GTX25370
Insulin Receptor beta antibody [CT-1]
Cannot supply to this region.
- SKU:
- GTX25370
- Additional Names:
- insulin receptor , CD220 , HHF5
- Application:
- ELISA, IP
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Unpurified
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Genetex
- Host:
- Mouse
- Reactivities:
- Human, Mouse, Rat
- Immunogen:
- A 15-mer synthetic peptide corresponding to aa Tyr-KKNGRILTLPRSNPS from the C-terminal of human insulin receptor B Beta-subunit
- Clone:
- CT-1
- Uniprot:
- P06213
- Synonyms:
- CD220;HHF5;insulin receptor;IR
- Extra Details:
- This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
- Shipping Conditions:
- Blue Ice