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  2. Polyclonal

GTX25300

NIPP1 antibody, C-term

Cannot supply to this region.

SKU:
GTX25300
Additional Names:
protein phosphatase 1 regulatory subunit 8 , ARD-1 , ARD1 , NIPP-1 , NIPP1 , PRO2047
Application:
WB, IHC-P
Concentration:
0.50 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Ammonium Sulfate Precipitated; Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Goat
Reactivities:
Human, Mouse
Buffer:
TBS, 0.5% BSA, 0.02% Sodium azide.
Immunogen:
Peptide with sequence C-EAWPGKKPTPSLLI, from the C Terminus of the protein sequence according to NP_002704.1; NP_054829.2; NP_612568.1.
Uniprot:
Q12972
Synonyms:
activator of RNA decay;ARD-1;ARD1;NIPP-1;NIPP1;nuclear inhibitor of protein phosphatase 1;nuclear inhibitor of protein phosphatase-1 alpha;nuclear inhibitor of protein phosphatase-1 beta;nuclear subunit of PP-1;PRO2047;Protein phosphatase 1 regulatory inhibitor subunit 8;protein phosphatase 1, regulatory (inhibitor) subunit 8;RNase E
Extra Details:
This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul 2008]
Shipping Conditions:
Blue Ice