GTX25272-PEP
USP20 blocking peptide
Cannot supply to this region.
- SKU:
- GTX25272-PEP
- Additional Names:
- Ubiquitin Specific Peptidase 20 , Lsfr3A , Vdu2 , Hvdu2 , Usp20
- Physical State:
- Lyophilized
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Buffer:
- Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
- Immunogen:
- ubiquitin specific peptidase 20
- Species:
- Human
- Synonyms:
- deubiquitinating enzyme 20;hVDU2;LSFR3A;pVHL-interacting deubiquitinating enzyme 2;ubiquitin carboxyl-terminal hydrolase 20;ubiquitin thioesterase 20;ubiquitin thiolesterase 20;ubiquitin-specific-processing protease 20;VDU2
- Extra Details:
- This gene encodes a ubiquitin specific processing protease that was first identified as a substrate of the VHL (von Hippel-Lindau disease) protein E3 ubiquitin ligase complex. In addition to being ubiquitinated by the VHL-E3 ligase complex, this enzyme deubiquitinates hypoxia-inducible factor (HIF)-1 alpha and thereby causes increased expression of HIF-1alpha targeted genes which play a role in angiogenesis, glucose metabolism, cell proliferation and metastasis. The enzyme encoded by this gene also regulates G-protein coupled receptor signaling by mediating the deubiquitination of beta-2 adrenergic receptor (ADRB2). This enzyme is a ubiquitously expressed thiolester hydrolase. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jan 2013]
- Shipping Conditions:
- Blue Ice