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  2. Polyclonal

GTX24816

Src (phospho Tyr416) antibody

Cannot supply to this region.

SKU:
GTX24816
Additional Names:
SRC proto-oncogene, non-receptor tyrosine kinase , ASV , SRC1 , THC6 , c-SRC , p60-Src
Application:
IHC, WB, IHC-P, IF, ICC, IP
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Bovine, Canine, Human, Mouse, Porcine, Rat, Yeast, Insect/Arthropod
Buffer:
PBS, 0.1% BSA, 50% Glycerol, 0.05% Sodium azide.
Immunogen:
Synthetic peptide derived from the region of Src that contains tyrosine 416 (tyrosine 417 including the initiating methionine). The sequence is conserved in human, mouse, rat, chicken and frog. The Tyr418 of human Src is equivalent to Tyr416 of chicken Src.
Uniprot:
P12931
Synonyms:
ASV;c-SRC;p60-Src;pp60c-src;proto-oncogene c-Src;proto-oncogene tyrosine-protein kinase Src;protooncogene SRC, Rous sarcoma;SRC1;THC6;tyrosine kinase pp60c-src;tyrosine-protein kinase SRC-1;v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
Extra Details:
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Shipping Conditions:
Blue Ice